GI Dynamics, Inc. Designates NOSC as Center of Excellence

GI Dynamics, Inc. Designates National Obesity Surgery Centre as Center of Excellence in the United Kingdom

Designation follows more than 12 months of product experience and notable patient outcomes

Lexington, Mass., United States and Sydney, Australia – Feb. 9, 2012 – GI Dynamics Inc. (ASX: GID) announced that it has designated the National Obesity Surgery Centre (NOSC) in Manchester, England as its newest Center of Excellence. This designation recognizes the success of the NOSC, which has been treating patients with the EndoBarrier since late 2010 in a post-market clinical study and later in commercial use.

“We’ve seen remarkable improvements in type 2 diabetes, weight loss and overall health in our commercial patients treated with the EndoBarrier,” said Prof. Nadey Hakim, general bariatric and transplant surgeon, National Obesity Surgery Centre, Manchester, England. “In contrast to other therapies, the EndoBarrier achieves these benefits without major surgery, which is a very important factor to many patients. We are pleased to be able to offer this breakthrough treatment more broadly.”

“The NOSC is one of the leading centers for weight loss and diabetes treatment in the U.K., and what we have seen with them is an excellent example of our commercialization strategy in action,” said Stuart A. Randle, president and chief executive officer, GI Dynamics. “With their experience in our post-market study and expanding commercial use of the EndoBarrier, we are delighted to designate the NOSC as a Center of Excellence. They have a knowledgeable team of skilled multidisciplinary experts and many patients who have been implanted with the EndoBarrier for 12 months with excellent results.”

The EndoBarrier is a thin, flexible, tube-shaped liner that forms a physical barrier between food and a portion of the wall of the intestine. It has been clinically proven to lower HbA1c levels, achieve weight loss of more than 20 percent and improve other important metabolic functions including cholesterol, blood pressure and triglycerides. Once implanted, the EndoBarrier affects certain gastrointestinal hormones involved glucose metabolism and satiety, and these changes allow for rapid and sustained improvement of type 2 diabetes1.

“For many years I have struggled to control my diabetes and weight, which had really started to take a toll on my quality of life and my overall well-being,” said Jenny Clarke, EndoBarrier patient treated at the NOSC. “I chose the EndoBarrier because I wanted to regain a good quality of life and I’m glad that I made this choice. Since having the EndoBarrier placed eight weeks ago, I’ve lost 30 pounds, my diabetes has improved and I’ve been able to reduce use of my diabetes medicines; but more importantly, I am active again. I’m now able to go for long walks, something I hadn’t been able to do for quite some time.”

“The EndoBarrier is an effective device that has positive impacts on patients with type 2 diabetes,” said Ajith M. George, M.D., MBBS, MRCP, consultant in diabetes and endocrinology working with the National Obesity Surgery Centre. “The EndoBarrier has not only demonstrated improvements in blood sugar control and weight loss, but also in other key metabolic functions including cholesterol levels, LDL and triglycerides. These are important benefits for people living with type 2 diabetes since all of these factors can contribute to the severity of the disease over time.”